The proliferation of LED drivers in general lighting applications places new requirements on system hardware, such as reduced component size to fit additional electronics in the same space, improved energy efficiency to perform within the same or lower thermal budget, connected and flexible architectures supporting multiple configurations, and accurate control that preserves LED light characteristics. In this white paper, we discuss the challenges for LED drivers in different applications such as high-power LED lighting, low/mid-power LED lighting, infrared (IR) diodes for machine vision systems, and low-power LED lighting.