This whitepaper delves into the unique application and selection considerations for medium voltage fuses, emphasizing their distinct role compared to lower voltage fuses. It provides descriptions, ratings, and application insights specifically focused on Littelfuse medium voltage fuses, directing readers to the Medium Voltage Fuse section of the Littelfuse POWR-GARD Catalog for comprehensive information. This paper also offers guidance on definitions and technical terms related to medium voltage fuses, facilitating informed decision-making in electrical system design.